Scientific category: LYMPHOID NEOPLASIA Title: A new biological prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma Authors:
نویسندگان
چکیده
Anamarija M. Perry, Teresa M. Cardesa-Salzmann, Paul N. Meyer, Luis Colomo, Lynette M. Smith, Kai Fu, Timothy C. Greiner, Jan Delabie, Randy D. Gascoyne, Lisa Rimsza, Elaine S. Jaffe, German Ott, Andreas Rosenwald, Rita M. Braziel, Raymond Tubbs, James R. Cook, Louis M. Staudt, Joseph M. Connors, Laurie H. Sehn, Julie M. Vose, Armando López-Guillermo, Elias Campo, Wing C. Chan, and Dennis D. Weisenburger
منابع مشابه
The Incidence of EBV in Diffuse Large B-Cell Lymphoma: A Comparative Study of Immunohistochemical and PCR Techniques
Background and Objectives: Epstein Barr Virus (EBV) is one of the members of herpesviridae family and a sub-category of Gamma herpes virinae. EBV, which normally has CR2 or CD21 receptors on B-lymphocytes, has mutagenic features for them. The virus plays an important role in causing some malignant cancers. About 30% of the cases with non-Hodgkin’s lymphoma are diffuse large B-cell l...
متن کاملLYMPHOID NEOPLASIA A new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma
Anamarija M. Perry,1 *Teresa M. Cardesa-Salzmann,2 *Paul N. Meyer,1 Luis Colomo,2 Lynette M. Smith,3 Kai Fu,1 Timothy C. Greiner,1 Jan Delabie,4 Randy D. Gascoyne,5 Lisa Rimsza,6 Elaine S. Jaffe,7 German Ott,8 Andreas Rosenwald,9 Rita M. Braziel,10 Raymond Tubbs,11 James R. Cook,12 Louis M. Staudt,13 Joseph M. Connors,14 Laurie H. Sehn,14 Julie M. Vose,15 Armando López-Guillermo,16 Elias Campo,...
متن کاملAuthors and Affiliations
This is an author produced version of a paper published in Leukemia & Lymphoma. This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. "CD40 is a potential marker of favorable prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy." Access to the published version may require journal subscription. Pub...
متن کاملA new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma.
Biologic factors that predict the survival of patients with a diffuse large B-cell lymphoma, such as cell of origin and stromal signatures, have been discovered by gene expression profiling. We attempted to simulate these gene expression profiling findings and create a new biologic prognostic model based on immunohistochemistry. We studied 199 patients (125 in the training set, 74 in the valida...
متن کاملBCL2 Family Related Genes Expression and Chemotherapy Response in Diffuse Large B-Cell Lymphoma
Background and Objective: Approximately half of patients with diffuse large B-cell lymphoma are cured with current chemotherapy regimens. The purpose of this study was to evaluate Bax and Bcl2 expression and their relationship with the response to chemotherapy. Materials and Methods This study was a prospective analysis on 44 patients with diffuse large B-cell lymphoma. Their specimens we...
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تاریخ انتشار 2012